Failure of Concurrent Chemoradiotherapy for Organ Preservation in Laryngeal Cancer: Survival Outcomes and Recurrence Patterns
نویسندگان
چکیده
منابع مشابه
Concurrent chemoradiotherapy for organ function preservation in advanced patients with hypopharyngeal and laryngeal cancer.
Preservation of the larynx is the most critical factor influencing quality of life in the treatment of head and neck cancer. This clinical study focuses on laryngeal function-preserving chemoradiotherapy for locally advanced hypopharyngeal and laryngeal cancer. Thirty-two resectable cases with histologically proven squamous cell carcinoma undergoing function-preserving therapy were examined. In...
متن کاملSurvival Outcomes and Toxicity of Concurrent Chemoradiotherapy for Esophageal Cancer
Aims: The aim of the study was to investigate the impact of chemoradiotherapy(CRT) on survival of patients with unresectable esophageal cancer treated with radiotherapy combined with either concurrent DCF [docetaxel, cisplatin +5-fluorouracil(5-FU)] or CF [cisplatin and 5-FU).Patients and methods:Data of patients who underwent CRT for esophageal cancer during 2010 and 2015 in the department of ...
متن کاملOrgan preservation surgery for laryngeal cancer
The principles of management of the laryngeal cancer have evolved over the recent past with emphasis on organ preservation. These developments have paralleled technological advancements as well as refinement in the surgical technique. The surgeons are able to maintain physiological functions of larynx namely speech, respiration and swallowing without compromising the loco-regional control of ca...
متن کاملConcurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer.
BACKGROUND Induction chemotherapy with cisplatin plus fluorouracil followed by radiotherapy is the standard alternative to total laryngectomy for patients with locally advanced laryngeal cancer. The value of adding chemotherapy to radiotherapy and the optimal timing of chemotherapy are unknown. METHODS We randomly assigned patients with locally advanced cancer of the larynx to one of three tr...
متن کاملFunctional organ preservation for laryngeal cancer: past, present and future.
OBJECTIVE Management of laryngeal cancer has focused on improving survival while preserving function. Over the past 20 years, the trends have shifted from surgery to chemoradiotherapy and presently we are facing various challenges. It is imperative to re-examine what has happened and what can be done. METHODS Review of the literature along with our experience in the management of functional o...
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ژورنال
عنوان ژورنال: Ear, Nose & Throat Journal
سال: 2019
ISSN: 0145-5613,1942-7522
DOI: 10.1177/0145561319839788